Confidence with just one dose1,2

RUCONEST®: fast,1-4 effective,1,2 sustained relief5 for acute HAE attacks in just one dose1,2

RUCONEST® is indicated for the treatment of acute angioedema attacks in adults, adolescents, and children (aged 2 years and above) with hereditary angioedema (HAE) due to C1 esterase inhibitor deficiency.

HAE Background

HAE arises from a deficiency in functional C1 esterase inhibitor (C1-INH), which can have potentially life threatening implications.6,7

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Ruconest® Overview

RUCONEST® uses recombinant technology to restore C1-INH levels in the blood, targeting the root cause of HAE attacks.8-10

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Ruconest® Efficacy

RUCONEST®: fast,1,3,4 effective,1 sustained relief4,5 for acute HAE attacks in just one dose1,2

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Ruconest® is generally well tolerated based on both clinical and patient registry data.1,3,11,12

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RUCONEST® Patient Response

RUCONEST® has proven efficacy in children, patients with a higher body mass index (BMI), and is suitable for emergency room use.1,2-5,13-15

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Patient Profiles

How can RUCONEST® help your patients achieve their treatment goals?

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  1. Li H, et al. J Allergy Clin Immunol Pract 2015;3(3):417-423.
  2. Valerieva A, et al. World Allergy Organ J 2021;14(4):100535.
  3. Riedl M, et al. Ann Allergy Asthma Immunol 2013;110:295-299.
  4. Riedl M, et al. Ann Allergy Asthma Immunol 2014;112(2):163-169.
  5. Bernstein J, et al. Ann Allergy Asthma Immunol 2017;118(4):452-455.
  6. Cancian M, et al. Pediatr Allergy Immunol 2020;31 Suppl 24:22-24.
  7. European Value Dossier: RUCONEST. in the management of Acute Hereditary Angioedema. IQVIA, 2018.
  8. Riedl M. Clin Drug Investig 2015;35(7):407-417.
  9. van Veen H, et al. J Biotechnol 2012;162(2-3):319-326.
  10. Feussner A, et al. Transfusion 2014;54:2566-2573.
  11. Zuraw B, et al. J Allergy Clin Immunol 2010 Oct;126(4):821-827.
  12. Moldovan D, et al. Clin Exp Allergy 2012 Jun;42(6):929-935.
  13. Farrell C, et al. Br J Clin Pharmacol 2013;76(6):897-907.
  14. RUCONEST® SmPC. July 2023.
  15. Reshef A, et al. Pediatr Allergy Immunol. 2019;30(5):562-568.